The brand new season of Sanctuary picks up where season three left off, with Helen Magnus (Amanda Tapping) standing on a cobblestone street, far from her own time or the modern Sanctuary resources. Having followed her longtime nemesis Adam Worth (Ian Tracey) through a collapsing time vortex, she is stunned to realise they have both traveled back to London…1898. Worth is determined to change the course of his own history in order to save the life of his daughter - even at the risk of destroying the entire future – and Magnus must track him down and stop him before he can make changes too large to remedy.